Owen's daughter, Polly Stone, confirmed the actress' death to TMZ and said she died at her home in Vermont from ovarian cancer.
Owen played Marilyn Munster for the first 13 episodes of the series in 1964 but left to marry writer-producer Jon Stone, People reported. She was replaced by Pat Priest, who played the role in the series' final 57 episodes, according to IMDb.
Owen was born Beverley Ogg in Ottumwa, Iowa, on May 13, 1937, according to IMDb. After graduating from the University of Michigan, she moved to New York to pursue an acting career, according to the website.
She is survived by her two daughters, Polly and Kate.