Metro officials tweeted the bus driver on Route 75 was hit and was taken to Harborview Medical Center with non-life-threatening injuries.
The driver, 53-year-old Eric Stark, turned the bus around away from the suspect. Twelve passengers were on board and they were not injured.
Witness John Barrett described the scene to KIRO-TV.
"I was working in the garage (and) heard firecrackers,” Barrett said. “And then I opened the door, then I noticed the bus trying to back up extremely fast."
The suspect then approached another driver in a red Prius and opened fire. The driver, a man in his 50s, was pronounced dead at the scene.
Officers arrived at the scene and located the suspect but he got into the Prius and drove away at a high rate of speed.
As he fled, the suspect crashed into another vehicle. The 70-year-old driver in the other vehicle died in the crash.
After a brief standoff, officers took the suspect into custody.
The suspect, a Sand Point resident in his 30s, was taken to Harborview Medical Center with non-life-threatening injuries. He was under police guard Wednesday night.
The investigation remains ongoing.
Original story: Multiple people were shot Wednesday afternoon near Seattle's Lake City neighborhood, police said.
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The shooting happened near 120th Street and Sand Point Way Northeast after 4 p.m.
Four people, including a metro bus driver, were shot and one person was been detained, police said.
When KIRO-TV arrived at the scene, several vehicles and a Metro bus were involved.
King County Metro officials tweeted that a bus driver on Route 75 hit the emergency alarm, reporting that they had been shot. The injured driver was taken to Harborview Medical Center for treatment.
Twelve passengers were on board but they were not injured, initial reports indicated.
Police said one person was detained and KIRO-TV's news helicopter recorded another person being taken into custody when it flew over the scene.
Witness John Barrett described the scene.
"I was working in the garage, heard firecrackers. And then I opened the door, then I noticed the bus trying to back up extremely fast," Barrett said.